The design, development and clinical assessment of a new metacarpophalangeal joint prosthesis

类风湿性关节炎是一种严重的关节炎，影响着社区的许多人。它通常累及手部的手指关节，导致畸形、疼痛和随后的功能丧失。已经有用于手指关节置换的植入物，但不幸的是，这些植入物只有适度的好处，可能会断裂并导致进一步的关节破坏，导致畸形和疼痛的恶化。研制了一种用于手指关节置换的新型植入物。这种植入物有几个潜在的优势。首先，独特的设计在允许功能性运动的同时，防止类风湿疾病手指的复发畸形。其次，人们认为患者将更早恢复功能，并避免进一步的手指手术，因为这种植入物设计对周围组织的稳定性依赖较少。本研究的目的是探讨这种新型植入物在手指关节置换中的生物力学和临床应用效果。新的设计将经过特定的实验室测试，并用于临床试验，以量化它为类风湿性关节炎患者提供的治疗益处。

Rheumatoid arthritis is a crippling form of arthritis that affects many people in the community. It commonly involves the finger joints in the hands resulting in deformity, pain and subsequent loss of function. There have been implants designed for finger joint replacement, but unfortunately these implants have had only moderate benefits and can break and lead to further joint destruction resulting in the worsening of deformity and pain. A new implant for finger joint replacement has been developed. This implant has several potential advantages. Firstly the unique design acts to prevent recurring deformity in the fingers with rheumatoid disease while allowing functional motion. Secondly, it is thought that patients will return to function earlier and avoid the need for further finger surgery as this implant design relies less on the tissues around it for stability. The purpose of this study is to investigate the biomechanical and clinical benefits of this new implant for finger joint replacement. The new design will undergo specific laboratory tests and be used in a clinical trial to quantify the therapeutic benefits it provides to patients with rheumatoid arthritis.