The distinct neural signatures of motor neuron disease

运动神经元疾病的独特神经特征

• 批准号: nhmrc : GNT1162075
• 负责人: Dr Thanuja Dharmadasa
• 金额: $ 44.72万
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/distinct-neural-signatures-neuron-disease/1349356
• 关键词: distinct; neural; signatures; motor; neuron

Motor neuron disease (MND) is a progressive neurological disorder with no effective treatment. This project aims to characterise the evolution of MND from its earliest stage and identify how the disease spreads using state-of-the art brain imaging tools and functional assessments across two world-class facilities. This knowledge will improve early MND diagnosis, develop markers of disease activity, and tailor recruitment into therapeutic trials.

运动神经元疾病（MND）是一种进行性神经系统疾病，目前尚无有效的治疗方法。该项目旨在利用最先进的脑成像工具和两个世界一流设施的功能评估来描述运动神经元病从最早阶段的演变特征，并确定该疾病是如何传播的。这些知识将改善早期 MND 诊断，开发疾病活动标记，并调整治疗试验的招募。