The efficacy of adjunctive Garcinia mangostana Linn. pericarp for bipolar depression: A 24-week double-blind, randomized, placebo-controlled trial.

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Bipolar disorder, especially during episodes of depression, can be highly debilitating. There is scientific evidence now directing research towards new targets to produce new therapies for bipolar depression. The current study aims to utilise an entirely new agent made from the husk of the mangosteen fruit (mangosteen pericarp). Mangosteen pericarp has properties that we believe will assist in reducing symptoms for those with bipolar depression, when taken in addition to usual treatment.