Developing an adjunctive mobile application for co-morbid substance use and anxiety disorders: comprehensive user experience testing of the Unwinding Anxiety application

开发针对共病药物使用和焦虑症的辅助移动应用程序：Unwinding Anxiety 应用程序的综合用户体验测试

• 批准号: 10385945
• 负责人: William Nardi
• 金额: $ 4.68万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10385945
• 关键词: Address; Adult; Affect; Anxiety; Anxiety Disorders; Applications Grants; Caring; Clinical; Collection; Comprehensive Health Care; Custom; Data; Development; Distress; Eating Disorders; Emotional; Evidence based intervention; Evidence based treatment; Focus Groups; Funding; Future; Generalized Anxiety Disorder; Health; Health Technology; Individual; Integrative Therapy; Interview; Learning Module; Measures; Mental Health; Mobile Health Application; National Institute of Drug Abuse; Outcome; Participant; Pathway interactions; Patient-Focused Outcomes; Patients; Persons; Pharmacotherapy; Postdoctoral Fellow; Preparation; Psychotherapy; Quality of life; Recovery; Recovery Support; Reporting; Research; Research Design; Research Methodology; Resources; Role; Sampling; System; Testing; Therapeutic; Training; United States National Institutes of Health; Work; anxiety treatment; base; behavioral health; comorbidity; craving; design; digital; digital health; digital treatment; effectiveness testing; evidence base; experience; follow-up; health care settings; improved; informant; mHealth; mental health organization; mobile application; new technology; novel; patient oriented; polysubstance use; programs; psychoeducational; relapse risk; smoking cessation; social stigma; substance use; substance use treatment; treatment of anxiety disorders; treatment program; treatment strategy; usability; virtual

PROJECT SUMMARY Patients with comorbid substance use (SUD) and anxiety disorders (AD) have significantly poorer health outcomes than patients with SUD alone and experience increased risk for relapse. However, less than 10% engage in treatment and only 18% of SUD facilities and 9% of mental health organizations report the capacity to provide comprehensive care. Mobile health technologies have been increasingly applied for substance use and anxiety treatments in an effort to create more comprehensive, patient centered approaches to care. Despite increasing mobile application development, the majority of existing programs are designed to target SUD or anxiety individually, few utilize evidence-based content or are clinically validated, and the majority are not designed as integrative treatment components for patients with SUD-AD. The Unwinding Anxiety (UA) mobile app can fulfill this need as it delivers digital, evidence-based psychoeducational training in a manualized, scalable, and high-fidelity manner targeting mechanistic pathways consistent with previous research. The proposed research will comprehensively assess the user experiences of UA for individuals with SUD-AD who are in recovery and explore the role of exploratory behavioral and mental health outcomes (i.e., substance use, craving, anxiety) among 48 individuals in long term recovery (>6 months). We will utilize a convergent parallel mixed methods research study design involving the collection of both quantitative and qualitative measures concurrently. We will quantitatively investigate usability, feasibility, and fidelity using the Systems Usability Scale, educational module completion, and ecological check-in usage. Qualitatively we will collect data on usability of UA within a sub-sample of participants (n=18) conducting focused interviews weekly (4 x <30 min. sessions; n=18) and 3 focus groups (k=3; n=15). Our secondary aim is to determine the degree to which UA engages exploratory outcomes specifically substance use, craving, and anxiety in preparation for future trials. Completion of this study will result in: (1) comprehensive range of customizations grounded in patients lived experience which will be used to refine one of the first mobile applications for patients with SUD-AD serving as a scalable, evidence-based adjunctive therapy; (2) provide preliminary data for a post-doctoral NIH grant application testing this customized mobile application to improve adjunctive therapies for SUD-AD treatment.

项目概要 患有共病物质使用（SUD）和焦虑症（AD）的患者健康状况明显较差 与单独接受 SUD 的患者相比，其结果并经历了更高的复发风险。但不足10% 参与治疗，只有 18% 的 SUD 机构和 9% 的精神卫生组织报告有能力 提供全面的护理。移动医疗技术越来越多地应用于物质使用和 焦虑治疗旨在创造更全面、以患者为中心的护理方法。尽管 随着移动应用程序开发的不断增加，大多数现有程序都是针对 SUD 或 个别焦虑，很少有人使用基于证据的内容或经过临床验证，大多数都没有 设计作为 SUD-AD 患者的综合治疗组件。缓解焦虑 (UA) 手机 应用程序可以满足这一需求，因为它以手动、基于证据的方式提供数字化、基于证据的心理教育培训。 可扩展的、高保真度的方式针对与之前的研究一致的机制途径。这 拟议的研究将全面评估患有 SUD-AD 的个人的 UA 用户体验 正在康复并探索探索性行为和心理健康结果（即物质使用、 48 名处于长期恢复期（>6 个月）的个体中存在渴求、焦虑）。我们将利用收敛并行 混合方法研究设计涉及定量和定性测量的收集 同时。我们将使用系统可用性量表定量研究可用性、可行性和保真度， 教育模块完成，生态签到使用。我们将定性地收集有关可用性的数据 UA 在参与者子样本 (n=18) 中每周进行重点访谈（4 次 <30 分钟的会议； n=18）和 3 个焦点小组（k=3；n=15）。我们的次要目标是确定 UA 参与的程度 探索性结果，特别是物质使用、渴望和焦虑，为未来的试验做准备。完成 这项研究的结果将是：（1）基于患者生活经验的全面定制 它将用于完善 SUD-AD 患者的首批移动应用程序之一，作为可扩展的、 循证辅助治疗； (2) 为博士后NIH资助申请测试提供初步数据 这款定制的移动应用程序旨在改善 SUD-AD 治疗的辅助疗法。