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The interplay between viperin, peroxisomes and the cellular innate antiviral response

The interplay between viperin, peroxisomes and the cellular innate antiviral response
蝰蛇蛋白、过氧化物酶体和细胞先天抗病毒反应之间的相互作用
批准号:
nhmrc : 1145613
负责人:
A/Pr Michael Beard
金额:
$37.6万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2020-12-31

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中文摘要
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英文摘要
Infection with a virus initiates a cellular antiviral response that attempts to limit viral replication, however how this response is regulated is not well understood. In this proposal we will investigate a cellular protein (viperin) that can regulate this process by interaction with peroxisomes to amplify the antiviral response. This work will provide possible targets for therapeutic manipulation of the innate immune response that will be applicable to a wide range of viral infections.
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The interplay between viperin, peroxisomes and the cellular innate antiviral response
  • 批准号:
    nhmrc : GNT1145613
  • 项目类别:
    Project Grants
  • 资助金额:
    $55.61万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Michael Beard
  • 依托单位:
Hepatitis C infection and disease
  • 批准号:
    nhmrc : GNT1053206
  • 项目类别:
    Programs
  • 资助金额:
    $542.79万
  • 财政年份:
    2014
  • 负责人:
    A/Pr Michael Beard
  • 依托单位:
Hepatitis C infection: epidemiology, pathogenesis, and treatment
  • 批准号:
    nhmrc : 1053206
  • 项目类别:
    Program Grants
  • 资助金额:
    $379.74万
  • 财政年份:
    2014
  • 负责人:
    A/Pr Michael Beard
  • 依托单位:
Imaging the hepatitis C virus life cycle in real-time
  • 批准号:
    nhmrc : 1027641
  • 项目类别:
    Project Grants
  • 资助金额:
    $31.84万
  • 财政年份:
    2012
  • 负责人:
    A/Pr Michael Beard
  • 依托单位:
海外基金