Aspirin for the prevention of cognitive decline in the Elderly: a Neuro-Vascular Imaging Study (ENVIS-ion) from ASPREE

阿司匹林预防老年人认知能力下降：ASPREE 的神经血管成像研究 (ENVIS-ion)

• 批准号: nhmrc : 471460
• 负责人: A/Pr Mark Budge
• 金额: $ 89.43万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/aspirin-prevention-cognitive-ion-aspree/99753
• 关键词: Aspirin; prevention; cognitive; decline; Elderly

The ENVIS-ion trial will examine whether Aspirin is effective in delaying the onset of worsening of thinking and memory abilities in healthy older adults. Magnetic resonance imaging (MRI) of brain structure will detect markers of early worsening of thinking and memory abilities. Blood vessels in the back of the eye (retina) share many features with vessels in the brain. We will compare whether aspirin lessens changes over time of features shown with brain MRI and retinal photography.

envision试验将检验阿司匹林是否能有效延缓健康老年人思维和记忆能力的恶化。大脑结构的核磁共振成像（MRI）将发现早期思维和记忆能力恶化的标志。眼睛后部（视网膜）的血管与大脑中的血管有许多共同的特征。我们将比较阿司匹林是否会随着时间的推移减少脑MRI和视网膜摄影所显示的特征变化。