A Double Blind Randomised Placebo Controlled Trial of Melatonin as an Adjuvant Agent in Induction of Labour

褪黑素作为引产辅助剂的双盲随机安慰剂对照试验

• 批准号: nhmrc : GNT1123498
• 负责人: Dr Miranda Davies-Tuck
• 金额: $ 38.46万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/double-blind-randomised-induction-labour/1347350
• 关键词: Double; Blind; Randomised; Placebo; Controlled

Induction of labour, a common obstetric intervention fails in almost 40% of first time mothers. There is evidence to suggest that the endogenous hormone melatonin has important roles in the progress of labour. We will undertake a double-blind randomised placebo controlled trial of melatonin supplementation to improve the success of induction of labour in first time mothers. We will also assess the economic impact of melatonin supplementation at induction of labour.

引产是一种常见的产科干预措施，但在近40%的第一次生育的母亲中失败。有证据表明内源性褪黑激素在分娩过程中起重要作用。我们将进行一项双盲随机安慰剂对照试验，补充褪黑激素，以提高第一次母亲引产的成功率。我们还将评估在引产时补充褪黑激素的经济影响。