Are large joint osteoarthritis and low back pain metabolic disorders?

大关节骨关节炎和腰痛是代谢紊乱吗？

• 批准号: nhmrc : 1073284
• 负责人: Dr Andrew Teichtahl
• 金额: $ 25.47万
• 依托单位: Baker IDI Heart and Diabetes Institute
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/large-joint-osteoarthritis-metabolic-disorders/455551
• 关键词: large; joint; osteoarthritis; low; back

While osteoarthritis (OA) is considered a “wear and tear” disease, there is evidence that OA may be related to a cluster of metabolic abnormalities including obesity, diabetes mellitus, hypertension and high cholesterol. Similarly, low back pain main be linked to a sedentary lifestyle and metabolic changes. This project will examine the relationship between metabolic derangements and back pain and large joint OA in an attempt to better understand these diseases and develop effective treatments.

虽然骨关节炎（OA）被认为是一种“磨损”疾病，但有证据表明，OA可能与一系列代谢异常有关，包括肥胖、糖尿病、高血压和高胆固醇。同样，腰痛主要与久坐不动的生活方式和代谢变化有关。该项目将研究代谢紊乱与背痛和大关节OA之间的关系，以更好地了解这些疾病并开发有效的治疗方法。