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The novel role of eukaryotic elongation factor 2 kinase (eEF2K) in atherosclerosis

The novel role of eukaryotic elongation factor 2 kinase (eEF2K) in atherosclerosis
真核延伸因子2激酶(eEF2K)在动脉粥样硬化中的新作用
批准号:
nhmrc : 1142794
负责人:
Dr Peter Psaltis
金额:
$43.98万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2020-12-31

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中文摘要
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英文摘要
Atherosclerosis causes build up of cholesterol plaques inside blood vessels that cause heart attacks and strokes. Macrophages are a type of cell that accumulate inside these plaques to make them grow. We work with a molecule called eukaryotic elongation factor 2 kinase (eEF2K), that controls how cells in the body divide and survive. We are studying how eEF2K controls the macrophage build up in plaque to develop new treatments against atherosclerosis that can stop heart attacks and strokes.
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New approaches to target plaque inflammation in atherosclerosis
  • 批准号:
    nhmrc : GNT1161506
  • 项目类别:
    Career Development Fellowships
  • 资助金额:
    $38.67万
  • 财政年份:
    2019
  • 负责人:
    Dr Peter Psaltis
  • 依托单位:
Bone marrow macrophages: “Resident Evil” in the establishment and progression of multiple myeloma
  • 批准号:
    nhmrc : 1140996
  • 项目类别:
    Project Grants
  • 资助金额:
    $38.58万
  • 财政年份:
    2018
  • 负责人:
    Dr Peter Psaltis
  • 依托单位:
The novel role of eukaryotic elongation factor 2 kinase (eEF2K) in atherosclerosis
  • 批准号:
    nhmrc : GNT1142794
  • 项目类别:
    Project Grants
  • 资助金额:
    $65.05万
  • 财政年份:
    2018
  • 负责人:
    Dr Peter Psaltis
  • 依托单位:
A study of the plaque-modifying actions of colchicine in stable and unstable atherosclerosis: from mouse models to clinical imaging.
  • 批准号:
    nhmrc : 1127159
  • 项目类别:
    Project Grants
  • 资助金额:
    $81.88万
  • 财政年份:
    2017
  • 负责人:
    Dr Peter Psaltis
  • 依托单位:
国内基金
海外基金
PfAP2-R介导的PfCRT转录调控在恶性疟原虫对喹啉类药物抗性中的作用及机制研究
Sestrin2抑制内质网应激对早产儿视网膜病变的调控作用及其机制研究
  • 批准号:
    82371070
  • 项目类别:
    面上项目
  • 资助金额:
    49.00万元
  • 批准年份:
    2023
  • 负责人:
    赵培泉
  • 依托单位: