The prophylactic hypothermia to lessen traumatic brain injury-randomised controlled trial : Continuation of funding request

预防性低温可减轻创伤性脑损伤-随机对照试验：继续资助请求

• 批准号: nhmrc : 1121037
• 负责人: A/Pr Jeffrey Presneill
• 金额: $ 18.1万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/prophylactic-hypothermia-lessen-funding-request/946672
• 关键词: prophylactic; hypothermia; lessen; traumatic; brain

Traumatic brain injury (TBI) is a major cause of death and long term disability. About half with severe TBI will die or have a poor outcome. The social and economic costs to the community are high. Treatment focuses on optimising oxygen and blood flow to the brain. Cooling may protect the brain. POLAR is a randomised trial of early cooling in patients with TBI. Cooling is started within 3 hours of injury. Data about the injury management and safety is collected. Recovery is measured at 6 months.

创伤性脑损伤（TBI）是造成死亡和长期残疾的主要原因。大约一半的严重脑外伤患者会死亡或预后不佳。社区的社会和经济成本很高。治疗的重点是优化氧气和血液流向大脑。降温可以保护大脑。POLAR是一项针对TBI患者早期降温的随机试验。受伤后3小时内开始降温。收集有关伤害管理和安全的数据。恢复期为6个月。