A randomised controlled trial of prophylactic hypothermia in severe traumatic brain injury.

严重创伤性脑损伤预防性低温的随机对照试验。

• 批准号: nhmrc : 545901
• 负责人: A/Pr Jeffrey Presneill
• 金额: $ 137.46万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/randomised-controlled-trial-brain-injury/81470
• 关键词: randomised; controlled; trial; prophylactic; hypothermia

Patients who suffer from a severe head injury (traumatic brain injury) have a 50% chance of having severe long term neurological disability or death. Some of this damage occurs after the initial injury and may be reduced by artificially lowering the body termperature for up to 7 days to protect the brain from further damage. This project will determine if early, sustained cooling is safe and if it can improve the long term neurological outcomes of patients with traumatic brain injury.

遭受严重头部损伤（创伤性脑损伤）的患者有50%的机会出现严重的长期神经功能残疾或死亡。有些损伤发生在最初的损伤之后，可以通过人为降低体温7天来保护大脑免受进一步的损伤。该项目将确定早期、持续冷却是否安全，以及它是否能改善创伤性脑损伤患者的长期神经预后。