Assessment of microcirculatory impairment in reperfused acute myocardial infarction by invasive coronary hemodynamic measurements and cardiac magnetic resonance imaging: modulation by exenatide

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This study aims to assess the health of small blood vessels of the heart muscle during and following a heart attack by measuring blood flow with a pressure wire and with cardiac magnetic resonance imaging. Small blood vessels within the heart muscle may become injured due to lack of oxygen and white cell activation during a heart attack. This study investigates the effect of a new agent, exenatide, on small blood vessels and white cells and determines whether it might lessen the degree of damage to heart muscle and small blood vessels.