A liquid protein platform for dynamic bio-inspired reaction compartments

该项目旨在通过生产具有一系列材料和结构特性的蛋白质液滴来研究液体蛋白质作为生物技术的一种新材料，并评估内在酶的活性。该项目将结合基于蛋白质的亚细胞超结构和酶蛋白质结构的概念，并应用尖端生物化学方法来研究如何通过液体蛋白质设计来控制和指导催化。预期成果包括使用蛋白质液滴设计动态催化隔间的新平台，强有力的国际和跨学科合作，以及为未来以绿色化学为基础的行业建立合成生物学工具和技术的知识库。

This project aims to investigate liquid protein as a novel material for biotechnology by producing protein droplets with a range of material and structural properties and assess the activity of internalised enzymes. The project will combine concepts from protein-based subcellular super-structure and enzyme protein structure and apply cutting-edge biochemistry methods to study how catalysis can be controlled and directed through liquid protein design. Expected outcomes include a new platform for using protein droplets to engineer dynamic catalytic compartments, strong international and interdisciplinary collaborations, and a knowledge-base for building synthetic biology tools and technologies for future green chemistry-based industries.