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Detection and inactivation of porcine parvovirus in pharmaceutical ingredients

Detection and inactivation of porcine parvovirus in pharmaceutical ingredients
药物成分中猪细小病毒的检测和灭活
批准号：
335018-2005
负责人：
Tijssen, Peter
金额：
$5.28万
依托单位：
Institut national de la recherche scientifique
依托单位国家：
加拿大
项目类别：
Collaborative Research and Development Grants
财政年份：
2006
资助国家：
加拿大
项目状态：
已结题
起止时间：
2006-01-01 至 2007-12-31
来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=325319
关键词：
Detectioninactivationporcineparvoviruspharmaceutical

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中文摘要
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英文摘要
To this date, many pharmaceutical products are manufactured from biological sources. When the products are derived from animal sources, it is essential to ensure the safety of the product by demonstrating the absence of viral contaminants. This study aims at developing methods to assay for a common pathogen of pigs known as porcine parvovirus (PPV). Although this virus has never been shown to infect humans, it is prudent to ensure its absence from purified materials used in drug products derived from porcine tissues. This study further aims at removing or inactivating residual virus particles found in those pharmaceutical preparations.
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