The development of protein and amino acid formulation strategies to reduce necrotic enteritis in broiler chickens

减少肉鸡坏死性肠炎的蛋白质和氨基酸配方策略的开发

• 批准号: 335038-2005
• 负责人: Drew, Murray
• 金额: $ 4.78万
• 依托单位: University of Saskatchewan
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2006
• 资助国家: 加拿大
• 起止时间: 2006-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=325321
• 关键词: development; protein; amino; acid; formulation

Necrotic enteritis (NE) is a common disease of broiler chickens caused by the overgrowth of Clostridium perfringens in the intestinal tract. One of the factors which predisposes birds to NE is the amino acid content of the diet. The objective of this proposal is to determine factors associated with dietary amino acids which affect the populations of C. perfringens in the intestinal tract of broiler chickens. Specifically, we will investigate the effect of dietary amino acid balance, amino acid digestibility and the level of non-essential amino acids on intestinal populations of C. perfringens, gut morphology and gene expression. We will also investigate the effect of subclinical necrotic enteritis on bird growth performance. The results of this work will enhance our understanding of the relationship between dietary amino acids and intestinal bacterial populations and reduce our dependence on in-feed antibiotics for broiler production.

坏死性肠炎是由产气荚膜梭菌在肉鸡肠道内过度生长引起的一种常见病。使鸟类易患NE的因素之一是饮食中的氨基酸含量。本研究的目的是确定与膳食氨基酸相关的影响C.肉鸡肠道中的产气荚膜杆菌。具体而言，我们将研究日粮氨基酸平衡，氨基酸消化率和非必需氨基酸水平对肠道种群的影响。产气荚膜杆菌、肠道形态和基因表达。我们还将研究亚临床坏死性肠炎对禽类生长性能的影响。这项工作的结果将提高我们对日粮氨基酸和肠道细菌种群之间关系的理解，并减少我们对肉鸡生产中饲用抗生素的依赖。