Bioactive and biodegradable scaffold and novel graft source for the repair of large segmental bone defects

用于修复大节段骨缺损的生物活性和可生物降解支架和新型移植源

• 批准号: nhmrc : 1055575
• 负责人: Dr Devakara Epari
• 金额: $ 30.08万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Development Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/bioactive-biodegradable-scaffold-bone-defects/112476
• 关键词: Bioactive; biodegradable; scaffold; novel; graft

The treatment of large bone defects arising from trauma and tumour remains a challenge to orthopaedic surgeons. This project combines a well-established scaffold that can be custom-made to address patient specific requirements with a novel source of graft that can be harvested in significant volumes with minimal pain and morbidity. This novel tissue engineering approach will be evaluated in a previously established pre-clinical model that reflects the severity of challenging clinical scenarios.

创伤和肿瘤引起的大面积骨缺损的治疗仍然是骨科医生面临的挑战。该项目结合了一个成熟的支架，可以定制，以满足患者的具体要求与一个新的移植物来源，可以在最小的痛苦和发病率的显着量收获。将在先前建立的临床前模型中评价这种新型组织工程方法，该模型反映了具有挑战性的临床场景的严重程度。