Cardiovascular disease risk in the elderly

老年人心血管疾病风险

• 批准号: nhmrc : 404022
• 负责人: Prof Joseph Hung
• 金额: $ 15.6万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cardiovascular-disease-risk-elderly/96546
• 关键词: Cardiovascular; disease; risk; elderly

The proportion of the population over 65 years of age is increasing, and cardiovascular disease (CVD) is a leading cause of disability and death in this group of people. Angina, heart failure and stroke in elderly people often result in considerable disability and in many instances in a need for changed living circumstances such as admission to nursing homes. Consequently there is an important need to understand how to prevent and manage cardiovascular diseases in elderly people. Although CVD occurs much more frequently in older persons, much of the epidemiological information on CVD risk factors and risk estimation comes from studies of middle-aged populations. Recently there has been an increased focus on whether the established relationships hold or differ in the elderly. This has generated debate about the relative value and effectiveness of treating risk factors in elderly people. This study, which is based on comprehensive and long-term risk factor, mortality and morbidity data from the Busselton Health Study and Health in Men Study, will lead to a better understanding of classic and new CVD risk factors in older persons and will contribute positively to the debate about the relative value and effectiveness of attempting to modify risk factors in the elderly. Further, it will facilitate improved methods for CVD risk assessment in older people and hence assist in determining whether which preventive actions to implement in the elderly.

65岁以上的人口比例正在增加，心血管疾病（CVD）是这一人群残疾和死亡的主要原因。老年人的心绞痛、心力衰竭和中风往往导致相当大的残疾，在许多情况下需要改变生活环境，如入住疗养院。因此，有必要了解如何预防和管理老年人心血管疾病。虽然心血管疾病在老年人中发生得更频繁，但有关心血管疾病风险因素和风险估计的流行病学信息大多来自中年人群的研究。最近，人们越来越关注老年人的既定关系是否成立或不同。这引起了关于治疗老年人风险因素的相对价值和有效性的争论。这项研究是基于布塞尔顿健康研究和男性健康研究的全面和长期的危险因素，死亡率和发病率数据，将导致更好地了解老年人的经典和新的心血管疾病危险因素，并将积极促进关于试图改变老年人危险因素的相对价值和有效性的辩论。此外，它将有助于改善老年人心血管疾病风险评估的方法，从而有助于确定是否在老年人中实施预防措施。