CCRE in Spinal Pain, Injury and Health

脊椎疾病是澳大利亚肌肉骨骼疾病造成的最大社会和经济负担。这反映了当前的现实：病因仍不清楚；80%的人口受到影响；孤立的职业实施了令人震惊的一系列干预措施。CCRE旨在针对这些现实，通过支持创新的跨学科研究和培训，提高澳大利亚预防和管理脊柱疾病的能力。这个以社区和大学为基础的中心将与全国脊柱科学家网络合作，将非常成功的临床和基础研究人员联合起来，促进跨学科的临床研究人员培训，开发新的诊断和治疗方法，并将研究结果转化为社区。通过临床研究，该中心的目标是：(I)增进对脊柱疼痛生理学和病理生理学的了解(Ii)将基础研究成果转化为临床实践(Iii)建立协调的多学科研究以减轻脊柱疼痛的负担(Iv)预测和预防从急性到慢性状态的转变(V)培养新一代跨学科临床科学家(Vi)在临床前研究中快速评估新的治疗可能性(Vii)开发诊断和治疗的创新技术(Viii)鼓励澳大利亚新发现的商业化机会(Ix)鼓励社区用户参与研究计划(X)向患者传播新的发现和循证实践的信息，临床医生、保险公司、政府、科学界和更广泛的社区

Spinal complaints present the greatest social and economic burden of musculoskeletal conditions in Australia. This reflects current realities: the cause remains unknown; 80% of the population is affected; and isolated professions perform a staggering array of interventions. The CCRE aims to target these realities and improve Australia's capacity to prevent and manage spinal disorders by supporting innovative interdisciplinary research and training. This community- and university-based centre will align highly successful clinical and basic researchers in collaboration with a national network of spine scientists to foster interdisciplinary clinical researcher training, develop new diagnostics and therapeutics, and translate findings to the community. Through clinical research the centre aims to: (i) Advance understanding of physiology and pathophysiology of spinal pain (ii) Translate findings from basic research to clinical practice (iii) Establish coordinated multidisciplinary research to reduce the burden of spinal pain (iv) Predict and prevent the transition from acute to chronic states (v) Train a new generation of transdisciplinary clinical scientists (vi) Rapidly assess new treatment possibilities in pre-clinical studies (vii) Develop innovative technologies for diagnostics and therapeutics (viii) Encourage Australian commercialisation opportunities for new discoveries (ix) Encourage community-user participation in direction of research programs (x) Disseminate new findings and information of evidence-based practice to patients, clinicians, insurers, government and the scientific and wider community