Non-rigid modeling of the human musculoskeletal system
人体肌肉骨骼系统的非刚性建模
基本信息
- 批准号:227682-2006
- 负责人:
- 金额:$ 1.46万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2006
- 资助国家:加拿大
- 起止时间:2006-01-01 至 2007-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Soft tissues help to attenuate the transmission of impact induced forces through the body. However, most biomechanical models of the human musculoskeletal system do not consider soft tissue effects. One main reason for this is that the movement characteristics of soft tissues and bone relative to one another in living subjects are largely undocumented to date. Accurate estimates of the masses of segment soft tissues for living subjects are also very limited. This reduces the accuracy of any biomechanical model that is developed to quantify soft tissue effects as a result of impact. Therefore, improved estimates of soft tissue and bone mass magnitudes in living subjects (to be incorporated in biomechanical models) will be obtained for the upper and lower extremities and trunk. Tissue mass prediction equations will be developed based on simple segment anthropometrics, and validated against segment mass estimates obtained by Dual Photon X-ray Absorptiometry (DXA). Considerable gains in biomechanical model fidelity could be realized if person-specific soft and rigid tissue mass estimates were utilized in the analysis of the impact response of living subjects of varying ages and body types. The dynamic behaviour of the soft and rigid tissues following impact will be modeled using visco-elastic mechanical systems. A finite element model of the leg and foot will also be developed and tested in comparison. The role of local muscle fatigue on the segment response and muscle stiffness following impact will continue to be evaluated. Surface accelerometry will provide estimates of the magnitudes of transmitted forces through body segments and joints. The effects that soft tissues have on reducing the transmission of potentially injurious forces will be determined based on model outputs at joints such as the knee and elbow. Segment response variability will be evaluated by studying upper and lower extremity impacts that reflect genuine every day work and sport activities that can result in injury (e.g. falling on an outstretched hand, heel landings during running).
软组织有助于减弱冲击力通过身体的传递。然而,人体肌肉骨骼系统的大多数生物力学模型没有考虑软组织效应。其中一个主要原因是,迄今为止,活体中软组织和骨相对于彼此的运动特性基本上没有记录。活体中节段软组织质量的准确估计是这也非常有限。这降低了任何生物力学模型的准确性,该模型被开发用于量化作为撞击结果的软组织影响。因此,改善了对活体受试者中软组织和骨量大小的估计。(将纳入生物力学模型)。将根据简单的人体测量学分段建立组织质量预测方程,并与双光子X射线吸收测量法(DXA)获得的节段质量估计值进行了验证。如果在分析不同年龄和体型的活体受试者的撞击响应时使用针对个人的软组织和刚性组织质量估计值,则可以实现生物力学模型保真度的相当大的增益。弹性机械系统。还将开发腿和脚的有限元模型并进行比较测试。将继续评估局部肌肉疲劳对身体部分响应和肌肉刚度的作用。表面加速度测量将提供通过身体部分和关节传递的力的估计值。软组织对减少将根据膝关节和肘关节等关节处的模型输出确定潜在伤害力的传递。将通过研究反映真实日常工作和可能导致伤害的体育活动(例如摔倒在伸出的手上、跑步时脚跟着地)的上肢和下肢冲击来评估节段响应变化。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Andrews, David其他文献
Phase I trial using proteasome inhibitor bortezomib and concurrent temozolomide and radiotherapy for central nervous system malignancies.
- DOI:
10.1016/j.ijrobp.2008.08.050 - 发表时间:
2009-06-01 - 期刊:
- 影响因子:7
- 作者:
Kubicek, Gregory J.;Werner-Wasik, Maria;Machtay, Mitchell;Mallon, Gayle;Myers, Thomas;Ramirez, Michael;Andrews, David;Curran, Walter J., Jr.;Dicker, Adam P. - 通讯作者:
Dicker, Adam P.
Is the pub still the hub?
- DOI:
10.1108/09596111211226815 - 发表时间:
2012-01-01 - 期刊:
- 影响因子:11.1
- 作者:
Andrews, David;Turner, Simon - 通讯作者:
Turner, Simon
Improving the customer experience through consistency and effective service delivery in the United Kingdom public house sector
- DOI:
10.1108/bfj-07-2016-0326 - 发表时间:
2017-01-01 - 期刊:
- 影响因子:3.3
- 作者:
Andrews, David;Turner, Simon - 通讯作者:
Turner, Simon
Left ventricular remodelling in rheumatic heart disease - trends over time and implications for follow-up in childhood.
- DOI:
10.1186/s12872-023-03497-0 - 发表时间:
2023-09-15 - 期刊:
- 影响因子:2.1
- 作者:
MacDonald, Bradley;Tarca, Adrian;Causer, Louise;Maslin, Katie;Bruce, Di;Schreiber-Wood, Rachel;Kumar, Mohit;Ramsay, James;Andrews, David;Budgeon, Charley;Katzenellenbogen, Judith;Bowen, Asha C.;Carapetis, Jonathan;Friedberg, Mark K.;Yim, Deane - 通讯作者:
Yim, Deane
Small molecules reveal an alternative mechanism of Bax activation
- DOI:
10.1042/bcj20160118 - 发表时间:
2016-04-15 - 期刊:
- 影响因子:4.1
- 作者:
Brahmbhatt, Hetal;Uehling, David;Andrews, David - 通讯作者:
Andrews, David
Andrews, David的其他文献
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{{ truncateString('Andrews, David', 18)}}的其他基金
Soft and rigid tissue effects on shock propagation.
软组织和硬组织对冲击传播的影响。
- 批准号:
227682-2012 - 财政年份:2016
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Soft and rigid tissue effects on shock propagation.
软组织和硬组织对冲击传播的影响。
- 批准号:
227682-2012 - 财政年份:2015
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Soft and rigid tissue effects on shock propagation.
软组织和硬组织对冲击传播的影响。
- 批准号:
227682-2012 - 财政年份:2014
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Soft and rigid tissue effects on shock propagation.
软组织和硬组织对冲击传播的影响。
- 批准号:
227682-2012 - 财政年份:2013
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Soft and rigid tissue effects on shock propagation.
软组织和硬组织对冲击传播的影响。
- 批准号:
227682-2012 - 财政年份:2012
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Non-rigid modeling of the human musculoskeletal system
人体肌肉骨骼系统的非刚性建模
- 批准号:
227682-2006 - 财政年份:2010
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Non-rigid modeling of the human musculoskeletal system
人体肌肉骨骼系统的非刚性建模
- 批准号:
227682-2006 - 财政年份:2009
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Non-rigid modeling of the human musculoskeletal system
人体肌肉骨骼系统的非刚性建模
- 批准号:
227682-2006 - 财政年份:2008
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Non-rigid modeling of the human musculoskeletal system
人体肌肉骨骼系统的非刚性建模
- 批准号:
227682-2006 - 财政年份:2007
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Non-rigid modelling of the human musculoskeletal system
人体肌肉骨骼系统的非刚性建模
- 批准号:
227682-2001 - 财政年份:2005
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
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Non-rigid modeling of the human musculoskeletal system
人体肌肉骨骼系统的非刚性建模
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$ 1.46万 - 项目类别:
Non-rigid modeling of the human musculoskeletal system
人体肌肉骨骼系统的非刚性建模
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227682-2006 - 财政年份:2009
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
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人体肌肉骨骼系统的非刚性建模
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227682-2006 - 财政年份:2008
- 资助金额:
$ 1.46万 - 项目类别:
Discovery Grants Program - Individual
Non-rigid modeling of the human musculoskeletal system
人体肌肉骨骼系统的非刚性建模
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227682-2006 - 财政年份:2007
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