Discovering and developing new chemistry for phosphorus, arsenic, antimony and bismuth

发现和开发磷、砷、锑和铋的新化学物质

• 批准号: 1939-2006
• 负责人: Burford, Neil
• 金额: $ 7.65万
• 依托单位: Dalhousie University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2006
• 资助国家: 加拿大
• 起止时间: 2006-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=335871
• 关键词: Discovering; developing; new; chemistry; phosphorus

Discovery and development of new materials, catalysts and pharmaceuticals relies on the fundamental understanding of the way in which molecules are held together (structure and chemical bonding) and the way they react with other compounds (chemical reactivity).  An enormous database is available for the chemistry of carbon due to the direct importance of this element in life functions.  However, the chemistry of other elements is superficially developed in comparison.  The emerging importance of the pnictogen elements (phosphorus, arsenic, antimony and bismuth) in the discovery of effective inorganic pharmaceuticals, novel polymeric materials and new electronic materials, requires a thorough and comprehensive understanding of their fundamental chemistry.  We are investigating efficient and effective preparative or synthetic routes to new, fundamentally important molecules containing P, As, Sb or Bi, in which the pnictogen center exhibits an unusual local structure, is engaged in a new connectivity, or provides materials with new, spectroscopic, physical or reactivity properties. We are establishing new directions in the fundamental chemistry of the pnictogens and our research program is changing the way in which chemists consider the chemistry of the non-metal elements in general.  The pnictogens are especially interesting elements as they typically accommodate a lone pair of electrons, but can simultaneously carry a positive charge.  In this context, we are developing the coordination chemistry of electron-rich pnictogen centers as Lewis acceptors. The objectives of our research programs for 2006-2010 are the synthesis and characterization of compounds that represent: 1) Development of the coordination chemistry of pnictogen cation Lewis acceptors. 2) The synthesis and characterization of the first catena-polyphosphorus cations as a fundamental new direction in phosphorus chemistry. 3)  The preparation of extended systems derived from complexes of electron-rich pnictogen Lewis acceptors.

新材料、催化剂和药物的发现和开发依赖于对分子结合方式的基本理解（结构和化学键）以及它们与其他化合物反应的方式（化学反应性）。由于碳元素在生命功能中的直接重要性，可获得碳化学的巨大数据库。然而，相比之下，其他元素的化学性质发展得很肤浅。氮族元素的重要性正在显现，（磷、砷、锑和铋）在发现有效的无机药物、新型聚合物材料和新型电子材料方面的作用，需要对它们的基本化学有全面深入的了解。我们正在研究有效的制备或合成路线，以获得新的、具有根本重要性的含P、As、Sb或Bi的分子，其中氮族元素中心表现出不寻常的局部结构，参与新的连接性，或提供具有新的光谱、物理或反应性质的材料。我们在氮族元素的基础化学中建立了新的方向，我们的研究计划正在改变化学家考虑非金属元素化学的方式。氮族元素是特别有趣的元素，因为它们通常容纳一对孤电子，但同时可以携带正电荷。在这种情况下，我们正在发展富电子氮族中心作为刘易斯受体的配位化学。2006-2010年我们的研究计划的目标是合成和表征的化合物，代表：1）磷属元素阳离子刘易斯受体的配位化学的发展。2)第一链聚磷阳离子的合成与表征是磷化学的一个基本新方向。3)富电子氮族元素刘易斯受体配合物扩展体系的制备。