Characterisation of eating behaviour and metabolic phenotypes across neurodegenerative diseases: insights for survival and progression

神经退行性疾病饮食行为和代谢表型的特征：生存和进展的见解

• 批准号: nhmrc : 1120770
• 金额: $ 23.19万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/characterisation-eating-behaviour-survival-progression/946621
• 关键词: Characterisation; eating; behaviour; metabolic; phenotypes

It has been suggested that metabolic changes and eating behavior could modify the progression of neurodegeneration. This research aims using brain imaging, pathological examination and novel techniques from obesity research to examine if there are characteristic metabolic changes in patients with frontotemporal dementia, Amyotrophic lateral sclerosis and Alzheimer’s disease; how these changes relate to eating behavior, and how they may affect disease progression and survival.

已有研究表明，代谢变化和饮食行为可能会改变神经退行性变的进程。这项研究的目的是利用大脑成像、病理检查和肥胖症研究的新技术来检查额颞部痴呆、肌萎缩侧索硬化症和阿尔茨海默病患者是否存在特征性的代谢变化；这些变化与饮食行为有何关系，以及它们可能如何影响疾病的进展和生存。