CHARACTERIZATION AND PURIFICATION OF A NOVEL ANTI-HIV FACTOR

新型抗 HIV 因子的表征和纯化

• 批准号: nhmrc : 503807
• 负责人: Dr Amit Kapur
• 金额: $ 11.39万
• 依托单位: Sydney West Area Health Service
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Development Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/characterization-purification-novel-hiv-factor/101510
• 关键词: CHARACTERIZATION; PURIFICATION; NOVEL; ANTI; HIV

We have identified biological evidence for a novel anti-HIV factor in a patient who has not progressed to HIV disease in 22 years. We have identified active forms in a solution, which confer potent activity against HIV. This factor helps in creating the pool of specialized antigen presenting cells, which are vital to combating with HIV in vivo. We propose to characterize this factor biologically, proteomically and genomically.

我们已经确定了一种新的抗HIV因子的生物学证据，该因子存在于一名22年未进展为HIV疾病的患者身上。我们已经确定了一种溶液中的活性形式，具有抗艾滋病毒的有效活性。这一因素有助于形成专门的抗原呈递细胞池，这对于在体内对抗HIV至关重要。我们建议对这一因素进行生物学、蛋白质组学和基因组学表征。