Characterizing the molecular mechanisms of clinically important bacterial-fungal interactions; the potential to uncover novel therapeutic targets

表征临床上重要的细菌-真菌相互作用的分子机制；

• 批准号: nhmrc : 1010114
• 负责人: Prof Anton Peleg
• 金额: $ 32.04万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/characterizing-molecular-mechanisms-therapeutic-targets/109463
• 关键词: Characterizing; molecular; mechanisms; clinically; important

In hospitals and in nature, diverse microbes, such as bacteria and fungi, often live in close proximity to each other. Their interactions can either be helpful or detrimental to one another, and such interactions are likely important for their ability to cause human disease. This proposal aims to study the mechanisms by which bacteria interact with fungi and by doing so, will identify important mechanisms of how microbes cause human illness and also uncover new targets for antibiotic development.

在医院和自然界中，各种微生物，如细菌和真菌，经常彼此靠近。它们的相互作用可能对彼此有益或有害，这种相互作用可能对它们引起人类疾病的能力很重要。该提案旨在研究细菌与真菌相互作用的机制，通过这样做，将确定微生物如何引起人类疾病的重要机制，并发现抗生素开发的新靶点。