Mechanisms of Disease Caused by Hospital-acquired Pathogens

医院获得性病原体引起疾病的机制

• 批准号: nhmrc : 1047916
• 负责人: Prof Anton Peleg
• 金额: $ 31.02万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mechanisms-disease-caused-acquired-pathogens/111981
• 关键词: Mechanisms; Disease; Caused; Hospital; acquired

We are currently experiencing unprecedented levels of antibiotic resistance in human pathogens. Unfortunately, the drug development pipeline is drying up, with almost no novel therapeutic options expected in the near future. This proposal aims to identify the mechanisms by which the most important antibiotic-resistant human pathogens make us sick. The expected outcomes are the identification of new targets that may be amenable to future drug development. These targets are aimed at making the organisms less capable of causing disease in humans.

我们目前正在经历人类病原体前所未有的抗生素耐药性。不幸的是，药物开发管道正在枯竭，在不久的将来几乎没有新的治疗选择。该提案旨在确定最重要的耐药人类病原体使我们生病的机制。预期的结果是确定可能适合未来药物开发的新靶点。这些目标旨在降低生物体在人类中引起疾病的能力。