p53 and hepatocyte proliferation in chronic liver disease

p53 与慢性肝病中的肝细胞增殖

• 批准号: nhmrc : 1059488
• 负责人: Prof Narcissus Teoh
• 金额: $ 22.1万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/p53-hepatocyte-proliferation-liver-disease/454760
• 关键词: p53; hepatocyte; proliferation; chronic; liver

The aim of this project is understand how loss of control of p53, a tumour suppressor gene, in liver cells causes the transformation of normal liver cell (hepatocyte) to ‘rouge’ pre-cancerous cells in hepatocellular carcinoma (HCC) or primary liver ca

该项目的目的是了解肝细胞中 p53（一种肿瘤抑制基因）的失控如何导致正常肝细胞（肝细胞）转变为肝细胞癌 (HCC) 或原发性肝癌中的“胭脂”癌前细胞。