CAN PRIORITY ALLOCATION OF DECEASED DONOR KIDNEYS BASED ON EPLET AND BROAD HLA-ANTIGEN MATCHING IMPROVE KIDNEY TRANSPLANT POTENTIAL, REDUCES IMMUNOGENICITY AND IMPROVE HEALTH OUTCOMES IN INDIGENOUS KIDNEY TRANSPLANT CANDIDATES?

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Although kidney transplantation has been shown to improve life expectancy in patients with chronic kidney disease (CKD), indigenous patients with CKD wait twice as long on the wait-list before transplant and have up to a 3-fold increased risk of rejection and infections resulting in graft loss and death respectively compared to non-indigenous patients. A better understanding of the immunological make-up of indigenous patients may help to reduce the risk of complications and improve survival.