A Randomised Trial of DHA in Pregnancy to Prevent Postnatal Depressive Symptoms and Enhance Neurodevelopment in Children

妊娠期 DHA 预防产后抑郁症状并增强儿童神经发育的随机试验

• 批准号: nhmrc : 349301
• 负责人: Dr Andrew Mcphee
• 金额: $ 109.96万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/randomised-trial-dha-neurodevelopment-children/100180
• 关键词: Randomised; Trial; DHA; Pregnancy; Prevent

Postnatal depression strikes 12-17% of women in the year after giving birth. Postnatal depression can result in emotional, behavioural and developmental problems in children. Although there are many complex psychological and social factors involved, supplementing the diet with an omega-3 fat called DHA has been shown to alleviate the symptoms of depression. Enriching diets with DHA has also been associated with improvements in visual and neural abilities of young infants. Normally, DHA is obtained through the mother's diet and is then passed onto the developing baby whilst in the womb. However, the amount of DHA that is delivered to the baby in pregnancy is high, and in most cases is far higher than most Australian mothers get in their diets. In this study we will test whether supplementing the diets of pregnant women with DHA results in women suffering less depressive symptoms and children with better development scores. If our study is successful, it will result in a simple and effective way to prevent postnatal depression and improve the developmental outcome of the children.

12-17%的妇女在产后一年内患上产后抑郁症。产后抑郁症可导致儿童出现情绪、行为和发育问题。虽然有许多复杂的心理和社会因素参与，补充饮食与欧米茄-3脂肪称为DHA已被证明可以缓解抑郁症的症状。富含DHA的饮食也与幼儿视觉和神经能力的改善有关。通常，DHA是通过母亲的饮食获得的，然后在子宫内传递给发育中的婴儿。然而，在怀孕期间传递给婴儿的DHA含量很高，在大多数情况下远远高于大多数澳大利亚母亲从饮食中获得的DHA。在这项研究中，我们将测试在孕妇的饮食中补充DHA是否会导致妇女遭受更少的抑郁症状和儿童更好的发育评分。如果我们的研究成功，将为预防产后抑郁症和改善儿童的发育结果提供一种简单有效的方法。