Regulation of cell proliferation by the actin cytoskeleton

肌动蛋白细胞骨架对细胞增殖的调节

• 批准号: nhmrc : 1004175
• 负责人: Dr Galina Schevzov
• 金额: $ 40.53万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/regulation-cell-proliferation-actin-cytoskeleton/109011
• 关键词: Regulation; cell; proliferation; actin; cytoskeleton

The architecture of cells defines both their shape and function. It has been known for a long time that cell architecture controls the growth of cells and in particular their capacity to proliferate. We have identified part of the architectural system which controls this process. In this project we will establish how this works and its role in the body. This research will test whether this part of the cell�s architecture is a suitable drug target for the treatment of disorders in cell growth.

细胞的结构决定了它们的形状和功能。长期以来，人们已经知道细胞结构控制细胞的生长，特别是它们的增殖能力。我们已经确定了控制这一过程的建筑系统的一部分。在这个项目中，我们将确定它是如何工作的，以及它在身体中的作用。这项研究将测试细胞结构的这一部分是否是治疗细胞生长障碍的合适药物靶点。