Molecular tagging to measure two-dimensional fluid velocity in microchannels

分子标记测量微通道中的二维流体速度

• 批准号: 358995-2008
• 负责人: Kostiuk, Larry
• 金额: $ 2.79万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2007
• 资助国家: 加拿大
• 起止时间: 2007-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=364749
• 关键词: Molecular; tagging; measure; two; dimensional

The equipment requested in this proposal offers a unique opportunity in the development of research in micro-fluidics.  Flow of liquid within micro-channels can be driven by pressure or electrical forces.  Characterizing this fluid motion experimentally is very challenging.  Typical techniques monitor the motion of particles seeded in the flow.  These particles however may not follow true fluid motion especially if the particles are of a size similar to the channel width.  Experimental data is needed to verify computational models which are the main tool for research on this type of flow.  The proposed equipment will be configured into a measurement system that will determine fluid velocity by tracking tagged fluorescent molecules.  The proposed system will have many unique features that will form a powerful experimental tool.  These features include, all optical access from one view port, the ability to write a fine, unique pattern of dots into the flow increasing measurement resolution and complete computer control of the system.  This style of measure cannot be purchased commercially and all equipment has been specifically specified for the unique conditions found in micro-channel flows.

本提案中所要求的设备为微流体研究的发展提供了一个独特的机会。微通道内的液体流动可以由压力或电动力驱动。对这种流体运动进行实验表征是非常具有挑战性的。通常的技术是监测在流动中播种的颗粒的运动。然而，这些颗粒可能不遵循真正的流体运动，特别是当颗粒的大小与通道宽度相似时。需要实验数据来验证计算模型，这些计算模型是研究这种类型流动的主要工具。建议的设备将被配置为一种通过跟踪标记的荧光分子来确定流体速度的测量系统。建议的系统将具有许多独特的功能，将形成一个强大的实验工具。这些功能包括，从一个观察端口进行全光学访问，能够将精细、独特的网点图案写入流量中，提高了测量分辨率并完全由计算机控制系统。*这种类型的测量不能以商业方式购买，所有设备都已针对微通道流量中的独特条件进行了专门指定。