Remodelling in Cardiac Hypertrophy: Implications for Arrhythmogenesis

高血压(HBP)影响着三分之一的成年人。心肌肥大(心肌增厚)是高血压病的常见症状。这项研究试图研究心脏的电、结构和分子特性的潜在变化，这些变化可能导致与高血压和心肌肥厚相关的猝死和房颤(心律不齐)的增加。新的理解可能会确定新的治疗目标，以减少这些危及生命的疾病。

High blood pressure (HBP) affects 1 in 3 adults. Cardiac hypertrophy (thickened heart muscles) is a common condition seen in HBP. This research seeks to study the underlying changes in electrical, structural and molecular properties of the heart that may contribute to the increased sudden death and atrial fibrillation (irregular heart rhythm) associated with both HBP and cardiac hypertrophy. The new understanding may identify new treatment targets to reduce these life-threatening conditions.