Mapping in Atrial Fibrillation: A 3-dimensional Electrophysiological Evaluation of the Electro-pathological Substrate

心房颤动的映射：电病理基质的 3 维电生理学评估

• 批准号: nhmrc : 1016741
• 负责人: Dr Dennis Lau
• 金额: $ 27.8万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mapping-atrial-fibrillation-pathological-substrate/109806
• 关键词: Mapping; Atrial; Fibrillation; dimensional; Electrophysiological

Atrial fibrillation is the most frequently encountered heart rhythm disorder. However, mechanisms underlying the progressive nature of this disease remain poorly understood. This study aims to characterize the 3-D electrical dissociation and its relation to pathological changes in conditions predisposing to atrial fibrillation. This knowledge will facilitate the development of individualized, substrate-oriented pharmacological treatment and targeted therapeutic procedures for atrial fibrillation.

心房颤动是最常见的心律失常。然而，这种疾病的进展性的机制仍然知之甚少。本研究的目的是表征3-D电分离及其与易患心房颤动的条件下的病理变化的关系。这些知识将促进房颤的个体化、基质导向的药理学治疗和靶向治疗程序的发展。