Remote ischaemic preconditioning and its effect on coronary physiology and platelet and leukocyte activation.

远程缺血预处理及其对冠状动脉生理学以及血小板和白细胞活化的影响。

• 批准号: nhmrc : GNT1094384
• 负责人: Dr Jerrett Lau
• 金额: $ 12.07万
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/remote-ischaemic-preconditioning-leukocyte-activation/1345946
• 关键词: Remote; ischaemic; preconditioning; its; effect

Remote ischaemic preconditioning (RIPC) is a novel treatment which can improve patient outcomes after a heart attack, undergoing coronary stenting or bypass surgery. The mechanisms by which RIPC confers this cardio-protection is not clear. We will study the effects of RIPC on platelet activity and the flow of blood in the arteries that supply the heart. Understanding RIPC may open new avenues for treatment of patients with coronary artery disease, one of the major causes of death in Australia.

远程缺血预处理（RIPC）是一种新型的治疗方法，可以改善心脏病发作、冠状动脉支架植入术或搭桥手术后的患者结局。RIPC赋予这种心脏保护的机制尚不清楚。我们将研究RIPC对血小板活性和供应心脏的动脉中血液流动的影响。了解RIPC可能为冠状动脉疾病患者的治疗开辟新的途径，冠状动脉疾病是澳大利亚的主要死亡原因之一。