Research Fellowship

研究奖学金

• 批准号: nhmrc : 1022688
• 负责人: A/Pr Ashley Buckle
• 金额: $ 45.06万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/research-fellowship/110205
• 关键词: Research; Fellowship

My research is aimed at understanding how the structure and dynamics of proteins dictates their function. I use X-ray crystallography to determine the shapes of proteins. Proteins are not static, however - they move in complicated ways, and often their motion is critical to their function (molecular motors, for example). It is very difficult to 'watch' this movement in the lab, so I use computer simulation to try to understand how proteins move.

我的研究旨在了解蛋白质的结构和动态如何决定它们的功能。我用X射线结晶学来确定蛋白质的形状。然而，蛋白质并不是静态的--它们以复杂的方式运动，而且它们的运动通常对它们的功能至关重要(例如，分子马达)。在实验室里很难‘观察’这种运动，所以我使用计算机模拟来试图了解蛋白质是如何运动的。