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Resetting the tipping point: Converting immune checkpoint non-responders into responders.

Resetting the tipping point: Converting immune checkpoint non-responders into responders.
重置临界点:将免疫检查点无反应者转变为反应者。
批准号:
nhmrc : 1103980
负责人:
Dr Anthony Bosco
金额:
$31.21万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2018-12-31

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中文摘要
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英文摘要
Although immunotherapy has recently shown a breakthrough in the treatment of lung cancers, with long-term full regression of the cancer in some patients, most patients unfortunately do not respond. In this proposal, we want to characterise the events that occur in a cancer that is cured by immunotherapy, while it regresses. By subsequently reinforcing those processes, we aim to tip the balance towards a response, thereby increasing the cure rate.
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会议论文
Waxing and waning of asthma during transition from the teens to adulthood: identification of immunophenotypic markers to predict disease trajectory and guide development of treatment strategies to prevent progression to chronicity
  • 批准号:
    nhmrc : GNT1080492
  • 项目类别:
    Project Grants
  • 资助金额:
    $71.38万
  • 财政年份:
    2015
  • 负责人:
    Dr Anthony Bosco
  • 依托单位:
Characterization of cellular inflammatory responses underlying acute viral bronchiolitis in infants
  • 批准号:
    nhmrc : 1047663
  • 项目类别:
    Project Grants
  • 资助金额:
    $38.89万
  • 财政年份:
    2013
  • 负责人:
    Dr Anthony Bosco
  • 依托单位:
Developmental-associated dysregulation of innate anti-microbial immunity in early life as a determinant of susceptibility to atopic asthma
  • 批准号:
    nhmrc : 1026411
  • 项目类别:
    Project Grants
  • 资助金额:
    $38.03万
  • 财政年份:
    2012
  • 负责人:
    Dr Anthony Bosco
  • 依托单位:
国内基金
海外基金
随机激励下热声系统的tipping现象与控制研究
  • 批准号:
    12302036
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    30万元
  • 批准年份:
    2023
  • 负责人:
    张晓钰
  • 依托单位: