课题基金 / 基金详情

Developmental-associated dysregulation of innate anti-microbial immunity in early life as a determinant of susceptibility to atopic asthma

Developmental-associated dysregulation of innate anti-microbial immunity in early life as a determinant of susceptibility to atopic asthma
生命早期先天抗微生物免疫的发育相关失调是特应性哮喘易感性的决定因素
批准号:
nhmrc : 1026411
负责人:
Dr Anthony Bosco
金额:
$38.03万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2014-12-31

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中文摘要
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英文摘要
Previous NHMRC-sponsored research from the applicants has demonstrated that one of the strongest risk factors for subsequent development of asthma is having chest infections during infancy that are so severe that they trigger symptoms of fever and wheeze. It is not known what predisposes susceptible infants to these severe infections, and this project will attempt to define the mechanisms of susceptibility.
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Resetting the tipping point: Converting immune checkpoint non-responders into responders.
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    2013
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