Respiratory motor impairment in health and disease

健康和疾病中的呼吸运动障碍

• 批准号: nhmrc : GNT1154213
• 负责人: Prof Jane Butler
• 金额: $ 64.92万
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/respiratory-motor-impairment-health-disease/1349125
• 关键词: Respiratory; motor; impairment; health; disease

With ageing, chronic obstructive pulmonary disease and tetraplegia, respiratory muscles are weak and the mechanics of the chest and lungs are altered. My research proposal and vision is to determine the contribution of impaired neural control to respiratory motor impairment with the aim to identify new targets for therapy and to trial the use of abdominal muscle stimulation to reduce respiratory morbidity and mortality in these populations.

随着年龄的增长，慢性阻塞性肺病和四肢瘫痪，呼吸肌变得虚弱，胸部和肺部的机制也发生了变化。我的研究计划和愿景是确定神经控制受损对呼吸运动障碍的贡献，目的是确定新的治疗目标，并尝试使用腹肌刺激来降低这些人群的呼吸系统发病率和死亡率。