The Role of CD30 Overexpression in CD30-positive Non-Hodgkins Lymphomas

CD30分子位于正常血细胞的表面，但在一种叫做淋巴瘤的癌症中，CD30浓度很高。CD30的表达水平可能决定癌细胞是否被正常防御机制杀死或能够不受控制地生长。我们正在研究CD30基因的控制元素，以了解当细胞癌变时控制是如何丧失的。这一认识可能导致控制淋巴瘤的治疗策略。

The CD30 molecule sits on the surface of normal blood cells, but in a type of cancer called Lymphoma, CD30 concentration is high. The level of expression of CD30 may determine if the cancer cell is killed by the normal defense mechanisms or is able to grow uncontrollably. We are studying the control elements of the CD30 gene to understand how control is lost when the cell becomes cancerous. This knowledge may lead to therapeutic strategies to control lymphoma.