The role of endometrial stem/progenitor cells in uterine biology and gynaecological disease, and their use in regenerative medicine

子宫内膜干/祖细胞在子宫生物学和妇科疾病中的作用及其在再生医学中的应用

• 批准号: nhmrc : 1042298
• 负责人: Prof Caroline Gargett
• 金额: $ 61.35万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-endometrial-stemprogenitor-regenerative-medicine/111452
• 关键词: role; endometrial; stem; progenitor; cells

The endometrial lining of the uterus rapidly grows and sheds each month in reproductive age women. My discovery of 2 types of endometrial stem cells has changed our understanding of how endometrium grows and how abnormalities in this process lead to gynaecological disease. This project will characterise the role of endometrial stem cells in endometriosis and examine how endometrial mesenchymal stem cells can be used as a cell-based therapy for pelvic organ prolapse.

育龄妇女子宫内膜每月快速生长和脱落。我发现的两种类型的子宫内膜干细胞改变了我们对子宫内膜如何生长以及这个过程中的异常如何导致妇科疾病的理解。本项目将探讨子宫内膜干细胞在子宫内膜异位症中的作用，并研究子宫内膜间充质干细胞如何用于盆腔器官脱垂的细胞治疗。