The role of extracellular matrix enzymes in influenza virus infection

细胞外基质酶在流感病毒感染中的作用

• 批准号: nhmrc : GNT1158951
• 金额: $ 50.21万
• 依托单位: Deakin University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-extracellular-matrix-virus-infection/1379054
• 关键词: role; extracellular; matrix; enzymes; influenza

There are currently two strategies employed to control influenza infection in humans: vaccines and antivirals. Traditionally these intervention strategies have targeted the virus. Recently host cell molecules known as 'ADAMTS” have been shown to affect disease outcomes following influenza virus infection. This proposal will investigate the contribution of these molecules to influenza virus pathogenesis and immunity.

目前有两种策略用于控制人类流感感染：疫苗和抗病毒药物。传统上，这些干预策略针对的是病毒。最近，被称为“ADAMTS”的宿主细胞分子已被证明影响流感病毒感染后的疾病结果。这项提案将调查这些分子对流感病毒致病和免疫的贡献。