Role of the IFN-induced helicase IFIH1 in type 1 diabetes

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Type 1 diabetes (T1D) is presently the most common chronic disease of childhood and is increasing, with incidence in children under five doubling over the last five years. Recent findings indicate the ifih1 gene is important in T1D. Our research aims to establish the contribution of this gene to the disease. It is hoped that recognition of relevant pathological molecules will allow identification of risk factors for disease development and, ultimately, targets for therapeutic intervention.