Role of the IFN-induced helicase IFIH1 in type 1 diabetes

1型糖尿病(T1D)目前是儿童最常见的慢性疾病，而且还在增加，五岁以下儿童的发病率在过去五年中翻了一番。最近的研究结果表明，IFIH1基因在T1D中起重要作用。我们的研究旨在确定这种基因对疾病的贡献。人们希望，对相关病理分子的识别将有助于确定疾病发展的危险因素，并最终确定治疗干预的目标。

Type 1 diabetes (T1D) is presently the most common chronic disease of childhood and is increasing, with incidence in children under five doubling over the last five years. Recent findings indicate the ifih1 gene is important in T1D. Our research aims to establish the contribution of this gene to the disease. It is hoped that recognition of relevant pathological molecules will allow identification of risk factors for disease development and, ultimately, targets for therapeutic intervention.