The role of a novel cytokine of the innate immune response in viral infection

先天免疫反应的新型细胞因子在病毒感染中的作用

• 批准号: nhmrc : 1011175
• 负责人: Dr Niamh Mangan
• 金额: $ 22.97万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-novel-cytokine-viral-infection/109558
• 关键词: role; novel; cytokine; innate; immune

Sexually transmitted infections represent a critical global health and socioeconomic problem with over 1 billion new cases per annum. I propose a world-first description of a new protein that has a protective role against herpes simplex virus (HSV) infection of female reproductive tract. This unique protein, called interferon epsilon, was discovered in our laboratory. This project will facilitate development of new therapeutic approaches of benefit in HSV-2 infection.

性传播感染是一个严重的全球健康和社会经济问题，每年有超过10亿新病例。我提出了世界上第一个描述一种新的蛋白质，它对女性生殖道的单纯疱疹病毒（HSV）感染具有保护作用。这种独特的蛋白质，叫做干扰素，是在我们的实验室里发现的。该项目将促进开发对2型单纯疱疹病毒感染有益的新治疗方法。