Microbial ecology of fungal viruses and hypovirulence

真菌病毒和低毒力的微生物生态学

• 批准号: 2929-2006
• 负责人: Boland, Gregory
• 金额: $ 2.81万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=388677
• 关键词: Microbial; ecology; fungal; viruses; hypovirulence

Fungal viruses are increasingly being recognized as an important and diverse group of infectious agents that affect the virulence, prevalence, and survival of their fungal hosts. Many fungi cause economically-important plant diseases in agriculture, horticulture, and forestry, and fungal viruses in these hosts represent an opportunity for improved development of molecular and biological strategies of disease management.  Research proposed within this proposal will examine the role of fungal viruses in the physiology and ecology of an important group of plant pathogens, Sclerotinia species. Physiological studies will identify fungal viruses that reduce the ability of plant pathogens to cause disease (e.g. hypovirulence), determine how these viruses interfere with the normal growth and development of their fungal hosts, and investigate why some infected fungi display symptoms of infection and others do not.  Ecological studies will determine the prevalence and distribution of fungal viruses in naturally-occurring populations of these plant pathogens, investigate the potential for spread of these viruses to other fungal species, and examine how these viruses spread and influence their fungal hosts in nature. Collectively, this research will contribute to the assessment of fungal viruses for molecular or biological strategies of plant disease management.

真菌病毒越来越被认为是一个重要的和多样化的组感染性病原体，影响其真菌宿主的毒力，流行和生存。许多真菌在农业、园艺和林业中引起具有重要经济意义的植物病害，这些宿主中的真菌病毒代表了改善疾病管理的分子和生物学策略的发展的机会。生理学研究将确定降低植物病原体致病能力的真菌病毒（例如，低毒力），确定这些病毒如何干扰其真菌宿主的正常生长和发育，并调查为什么有些受感染的真菌会显示感染症状，而有些则没有。生态学研究将确定真菌病毒在自然环境中的流行和分布，这些植物病原体的发生种群，调查这些病毒传播到其他真菌物种的潜力，并检查这些病毒如何传播和影响自然界中的真菌宿主。总的来说，这项研究将有助于评估真菌病毒的分子或生物学策略的植物病害管理。