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The role of Porphyromonas gingivalis outer membrane vesicle biogenesis in virulence and immunomodulation

The role of Porphyromonas gingivalis outer membrane vesicle biogenesis in virulence and immunomodulation
牙龈卟啉单胞菌外膜囊泡生物发生在毒力和免疫调节中的作用
批准号:
nhmrc : GNT1101935
负责人:
A/Pr Glen Scholz
金额:
$73.43万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --

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中文摘要
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英文摘要
Porphyromonas gingivalis is a keystone pathogen in chronic periodontitis. This bacterium exists as part of a biofilm on the surface of the tooth and selectively packages enzymes, toxins and antigens on to vesicles that penetrate host tissue and cause the inflammatory response that is associated with disease progression. In this study we will determine the host response to vesicles and determine the role of a specific protein in vesicle biogenesis.
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The role of Porphyromonas gingivalis outer membrane vesicle biogenesis in virulence and immunomodulation
  • 批准号:
    nhmrc : 1101935
  • 项目类别:
    Project Grants
  • 资助金额:
    $50.53万
  • 财政年份:
    2016
  • 负责人:
    A/Pr Glen Scholz
  • 依托单位:
Interferon Regulatory Factor 6: a novel epithelial-specific regulator of mucosal inflammation
  • 批准号:
    nhmrc : 628769
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $34.54万
  • 财政年份:
    2010
  • 负责人:
    A/Pr Glen Scholz
  • 依托单位:
Defining the role and contribution of Cdc37 to signal transduction and tumourigenesis by Src-family kinases
  • 批准号:
    nhmrc : 191501
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $27.43万
  • 财政年份:
    2002
  • 负责人:
    A/Pr Glen Scholz
  • 依托单位:
海外基金