Role of sphingolipid signalling in hepatic insulin resistance and its application in prediction of risk for type 2 diabetes and prediabetes
Role of sphingolipid signalling in hepatic insulin resistance and its application in prediction of risk for type 2 diabetes and prediabetes
鞘脂信号传导在肝脏胰岛素抵抗中的作用及其在预测 2 型糖尿病和糖尿病前期风险中的应用
批准号：
nhmrc : GNT1113527
负责人：
A/Pr Huandong Lin
金额：
$56.33万
依托单位国家：
澳大利亚
项目类别：
International Collaborations
财政年份：
2016
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2016-01-01 至 --
中文摘要
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英文摘要
Type 2 diabetes is expected to reach epidemic proportions in the coming decades. Prediabetes is usually unrecognized and constitutes a major public health concern that needs earlier interventions, because the majority of prediabetic subjects proceed to T2D. We have identified an enzyme that plays an important role in insulin signalling. The possibility is that the level or activity of this enzyme is a potential biomarker of the prediabetes state and could be also used as a target
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