The role of stem-progenitor cells in regeneration of mouse endometrium.

干祖细胞在小鼠子宫内膜再生中的作用。

• 批准号: nhmrc : 490995
• 负责人: Dr Tu'Uhevaha Kaitu'U-Lino
• 金额: $ 20.8万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-stem-progenitor-mouse-endometrium/115452
• 关键词: role; stem; progenitor; cells; regeneration

The endometrium (lining of the uterus) undergoes breakdown and re-growth each month as part of the menstrual cycle. This restorative process is not well understood. For the first time stem cells have been identified within human endometrium that are likely to be responsible for its remarkable regeneration. The aim of this project is to identify stem cells within the mouse endometrium, to use as a model to understand how the endometrium restores each month after menstruation.

作为月经周期的一部分，子宫内膜(子宫内层)每月经历分解和再生长。这一恢复性过程还没有得到很好的理解。首次在人类子宫内膜中发现了干细胞，这些干细胞很可能是子宫内膜显着再生的原因。这个项目的目的是鉴定小鼠子宫内膜内的干细胞，作为一个模型来了解月经后子宫内膜是如何恢复的。