The role of tumour-initiating cells in glioma

在西方世界，原发性脑瘤的总体发病率为每10万人中有10例。与许多其他肿瘤不同，这些肿瘤发生在所有年龄段的患者中，是儿童和年轻人中第二常见的肿瘤类型。大多数脑瘤仍然无法治愈。我们正在利用我们在神经干细胞研究领域的专业知识来表征导致治疗耐药的肿瘤细胞，最终目标是确定治疗干预的新靶点。

The overall incidence of primary brain tumours in the Western world is 10 per 100,000 people. Unlike many other tumours, these occur in patients of all ages and comprise the second most common tumour type among children and young adults. Most brain tumours remain incurable. We are using our expertise in the field of neural stem cell research to characterise tumour cells responsible for resistance to treatment, with the final goal of identifying new targets for therapeutic intervention.