Dimorphic growth and resting structure development in plant pathogenic verticillium species
植物致病黄萎病菌的二态性生长和休眠结构发育
基本信息
- 批准号:216879-2006
- 负责人:
- 金额:$ 1.27万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2008
- 资助国家:加拿大
- 起止时间:2008-01-01 至 2009-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Verticillium dahliae, V. albo-atrum, and V. longisporum are soilborne fungi that cause vascular wilt disease in a variety of annual crops and perennials that are grown commercially in Canada and worldwide, including tomato, potato, oilseed rape, and other brassica crops. The soil habitat of these pathogens, their inaccessibility during infection, and their ability to survive for many years in the soil, pose formidable challenges to disease control. Few verticillium wilt-resistant cultivars are available, and chemical fumigants, which reduce levels of V. dahliae in the soil, are environmentally harmful, and destroy beneficial soil microorganisms. Given the present and potential economic impact of the pathogen, new approaches to disease control must be considered. One approach with much potential for disease control is to specifically target, and interfere with, the molecular processes which are critical for the growth of Verticillum in the plant, and/or its survival in the soil. The proposed research program will focus on molecular and genetic studies of: 1) the development of the long-lived resting structures, microsclerotia or melanized mycelia, which are produced in dying plant tissues, and provide the primary source of disease inoculum, and 2) dimorphic growth (production of both yeast-like spores and mycelia), which occurs in liquid culture, and in the plant vascular system during infection. Previous studies have shown that V. dahliae carries a gene that encodes a hydrophobin protein which is required for microsclerotia production. The same gene has been identified in V. albo-atrum, which does not produce microsclerotia; the role of this gene in V. albo-atrum is therefore unknown. A comparison of expression in V. albo-atrum and V. dahliae of these genes, and their respective proteins, will be carried out using reporter genes, mutational, and biochemical analysis. In addition, DNA microarray analyses will be used to identify additional genes that are highly expressed during resting structure development and/or dimorphic growth. Such genes will be candidates for further characterization.
大丽轮枝菌(Verticillium dahliae)、白色轮枝菌(V. albo-atrum)和长孢轮枝菌(V. longisporum)是在加拿大和世界各地商业种植的多种一年生和多年生作物(包括番茄、马铃薯、油菜和其他芸苔属作物)中引起维管枯萎病的土传真菌。这些病原体的土壤生境、它们在感染期间的不可接近性以及它们在土壤中存活多年的能力,对病害控制提出了严峻的挑战。目前很少有抗黄萎病的品种,而化学熏蒸剂降低土壤中大丽轮枝菌的水平,对环境有害,并破坏有益的土壤微生物。鉴于病原体目前和潜在的经济影响,必须考虑新的病害控制方法。 其中一个很有潜力的疾病控制方法是专门针对和干扰Verticillum在植物中生长和/或在土壤中生存的分子过程。拟议的研究计划将集中在以下方面的分子和遗传研究:1)在垂死的植物组织中产生的长寿的休眠结构、微菌核或黑化菌丝体的发育,并提供疾病接种物的主要来源,以及2)二型生长(产生酵母样孢子和菌丝体),发生在液体培养中,先前的研究表明,大丽轮枝菌携带编码微菌核产生所需的疏水蛋白的基因。在不产生微菌核的V. albo-atrum中鉴定了相同的基因;因此,该基因在V. albo-atrum中的作用是未知的。将使用报告基因、突变和生物化学分析来比较这些基因在V. albo-atrum和V. dahliae中的表达,以及它们各自的蛋白质。此外,DNA微阵列分析将用于鉴定在静止结构发育和/或二态生长期间高表达的其他基因,这些基因将成为进一步表征的候选基因。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Dobinson, Katherine其他文献
Dobinson, Katherine的其他文献
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{{ truncateString('Dobinson, Katherine', 18)}}的其他基金
Characterization of the molecular pathways that direct development and pathogenicity in the vascular wilt fungus Verticillium dahliae
维管束枯萎病真菌大丽黄萎病指导发育和致病性的分子途径的表征
- 批准号:
216879-2012 - 财政年份:2014
- 资助金额:
$ 1.27万 - 项目类别:
Discovery Grants Program - Individual
Characterization of the molecular pathways that direct development and pathogenicity in the vascular wilt fungus Verticillium dahliae
维管束枯萎病真菌大丽黄萎病指导发育和致病性的分子途径的表征
- 批准号:
216879-2012 - 财政年份:2013
- 资助金额:
$ 1.27万 - 项目类别:
Discovery Grants Program - Individual
Characterization of the molecular pathways that direct development and pathogenicity in the vascular wilt fungus Verticillium dahliae
维管束枯萎病真菌大丽黄萎病指导发育和致病性的分子途径的表征
- 批准号:
216879-2012 - 财政年份:2012
- 资助金额:
$ 1.27万 - 项目类别:
Discovery Grants Program - Individual
Dimorphic growth and resting structure development in plant pathogenic verticillium species
植物致病黄萎病菌的二态性生长和休眠结构发育
- 批准号:
216879-2006 - 财政年份:2010
- 资助金额:
$ 1.27万 - 项目类别:
Discovery Grants Program - Individual
Dimorphic growth and resting structure development in plant pathogenic verticillium species
植物致病黄萎病菌的二态性生长和休眠结构发育
- 批准号:
216879-2006 - 财政年份:2009
- 资助金额:
$ 1.27万 - 项目类别:
Discovery Grants Program - Individual
Dimorphic growth and resting structure development in plant pathogenic verticillium species
植物致病黄萎病菌的二态性生长和休眠结构发育
- 批准号:
216879-2006 - 财政年份:2007
- 资助金额:
$ 1.27万 - 项目类别:
Discovery Grants Program - Individual
Dimorphic growth and resting structure development in plant pathogenic verticillium species
植物致病黄萎病菌的二态性生长和休眠结构发育
- 批准号:
216879-2006 - 财政年份:2006
- 资助金额:
$ 1.27万 - 项目类别:
Discovery Grants Program - Individual
Gene expression and pathogenicity in the vascular wilt fungus Verticillium dahliae
维管束枯萎病菌大丽黄萎病的基因表达和致病性
- 批准号:
216879-2001 - 财政年份:2005
- 资助金额:
$ 1.27万 - 项目类别:
Discovery Grants Program - Individual
Gene expression and pathogenicity in the vascular wilt fungus Verticillium dahliae
维管束枯萎病菌大丽黄萎病的基因表达和致病性
- 批准号:
216879-2001 - 财政年份:2003
- 资助金额:
$ 1.27万 - 项目类别:
Discovery Grants Program - Individual
Gene expression and pathogenicity in the vascular wilt fungus Verticillium dahliae
维管束枯萎病菌大丽黄萎病的基因表达和致病性
- 批准号:
216879-2001 - 财政年份:2002
- 资助金额:
$ 1.27万 - 项目类别:
Discovery Grants Program - Individual
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