Roles of integrin receptors and the Helicobacter pylori protein CagL in gastritis and gastric cancer

整合素受体和幽门螺杆菌蛋白 CagL 在胃炎和胃癌中的作用

• 批准号: nhmrc : 545983
• 负责人: Dr Terry Kwok
• 金额: $ 19.38万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/roles-integrin-receptors-gastric-cancer/81432
• 关键词: Roles; integrin; receptors; Helicobacter; pylori

How the bacterium Helicobacter pylori (Hp) causes gastritis and gastric cancer in the stomach is not well understood. Here we investigate the molecular languages used by Hp to deregulate the normal functions of the human stomach cells. The research outcomes will on one hand help us to better understand how Hp causes diseases, and on the other hand, facilitate the development of new antibiotics or treatment therapies to combat gastric cancers and gastritis.

幽门螺杆菌（Hp）是如何在胃中引起胃炎和胃癌的还不清楚。在这里，我们调查的分子语言所使用的幽门螺杆菌解除正常功能的人胃细胞。研究结果一方面有助我们更深入了解Hp如何致病，另一方面亦有助开发新的抗生素或治疗方法，以对抗胃癌和胃炎。