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Understanding how the Helicobacter pylori pilin protein CagL promotes gastric cancer

Understanding how the Helicobacter pylori pilin protein CagL promotes gastric cancer
了解幽门螺杆菌菌毛蛋白 CagL 如何促进胃癌
批准号:
nhmrc : GNT1148142
负责人:
Dr Terry Kwok
金额:
$66.78万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --

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中文摘要
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英文摘要
The bacterium Helicobacter pylori is a major cause of gastric cancer and chronic gastritis. The bacterial protein CagL is a key disease-causing protein of H. pylori and potent stimulant of host immune responses. This study aims to understand how this virulent bacterial protein promotes cancer development, and to identify novel therapeutic targets and diagnostic markers for better management of gastric cancer and other severe chronic gastric diseases.
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Understanding how the Helicobacter pylori pilin protein CagL promotes gastric cancer
  • 批准号:
    nhmrc : 1148142
  • 项目类别:
    Project Grants
  • 资助金额:
    $45.15万
  • 财政年份:
    2018
  • 负责人:
    Dr Terry Kwok
  • 依托单位:
Structural basis for Helicobacter pylori adhesion to host epithelial cells
  • 批准号:
    nhmrc : 1086227
  • 项目类别:
    Project Grants
  • 资助金额:
    $44.36万
  • 财政年份:
    2015
  • 负责人:
    Dr Terry Kwok
  • 依托单位:
Roles of integrin receptors and the Helicobacter pylori protein CagL in gastritis and gastric cancer
  • 批准号:
    nhmrc : 545983
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $19.38万
  • 财政年份:
    2009
  • 负责人:
    Dr Terry Kwok
  • 依托单位:
海外基金