SBP1 and altered structure and function of malaria-infected red blood cells

SBP1 与疟疾感染红细胞结构和功能的改变

• 批准号: nhmrc : 606447
• 负责人: Dr Mohandas Narla
• 金额: $ 29.31万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/sbp1-altered-structure-blood-cells/94452
• 关键词: SBP1; altered; structure; function; malaria

Malaria is a serious disease affecting half the world's population. Every year, more than a million people (mostly children) die as a result of being infected with malaria parasites. Our work will help us to understand how the parasites alter normal human red blood cells and make them stick in organs such as the brain. Preventing the red blood cells from becoming sticky with new drugs will open up new lines of attack to combat this devastating disease.

疟疾是一种影响世界一半人口的严重疾病。每年有100多万人（大多数是儿童）死于疟疾寄生虫感染。我们的工作将帮助我们了解寄生虫如何改变正常的人体红细胞，并使它们粘附在大脑等器官中。用新药防止红细胞变得粘稠，将为对抗这种毁灭性疾病开辟新的攻击路线。